The present study is the first to evaluate … a comprehensive lifestyle intervention that included a low-fat, whole-foods, plant-based diet, exercise, stress management, and group support meetings …. At 3 months, significant changes in diet with a reduction in calories, protein, fat, saturated fat, cholesterol, and so-dium intake and an increase in carbohydrates, fiber, vitamin A, vitamin C, calcium, and iron were observed
Allen et al. (2011) Reflections on developments in health promotion in the past quarter century from founding members of the american journal of health promotion editorial board
So many forces are converging—the limitations of high-tech medicine are becoming clearer …. intensive lifestyle changes could stop or reverse the progression of even severe coronary atheroscle-rosis …. comprehensive lifestyle changes could markedly improve angina …. comprehensive lifestyle changes may slow, stop, or even reverse the progression of early-stage prostate cancer
Park et al. (2011) Multivitamin Use and the Risk of Mortality and Cancer Incidence: The Multiethnic Cohort Study
Multivitamin/mineral supplements … people expect this type of supplement to improve their health. However, the efficacy of these supplements to prevent chronic disease or premature death is not proven, and the National Institutes of Health do not recommend multivitamin/mineral supplements for this purpose …. in the current study, there was no clear decrease or increase in mortality from all causes, cardiovascular diseases, or cancer among multivitamin supplement users. Moreover, the risk of morbidity from overall or major cancers did not differ between multivitamin users and nonusers
Ong et al. (2011) Maternal “junk-food” feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring
Individuals exposed to high-fat, high-sugar diets before birth have an increased risk of obesity in later life. Recent studies have shown that these offspring exhibit increased preference for fat, leading to suggestions that perinatal exposure to high-fat, high-sugar foods results in permanent changes within the central reward system that increase the subsequent drive to overconsume palatable foods.
Crowe et al. (2011) Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study
A higher intake of fruits and vegetables has been associated with a lower risk of ischaemic heart disease (IHD) …. assess the relation between fruit and vegetable intake and risk of mortality from IHD …. each 80 g increase in intake was associated with a significant reduction in the risk of IHD mortality of 15% for women …. reduction for men was smaller (2%) and not statistically significant …. Participants consuming at least eight portions (80 g each) of fruits and vegetables a day had a 22% lower risk of fatal IHD …. compared with those consuming fewer than three portions a day …. only three (Greece, Italy, and Spain) of the eight countries had a mean intake greater than 5 servings per day …. The grouping for vegetables did not include potatoes or dried beans due to the different carbohydrate and energy compositions of these plant foods
Gomez-Huelgas et al. (2011) Prevalence of cardiovascular risk factors in an urban adult population from southern Spain. IMAP Study
Cardiovascular diseases (CVD) are the main cause of mortality in Spain, accounting for 33% of all deaths …. the prevalence of obesity, diabetes, hypertension and hypercholesterolaemia in Spain have all risen over the past 20 years …. the highest child and adolescent obesity rates in Europe …. Over 60% were either overweight or obese, and 76.7% had a sedentary lifestyle … Above the age of 50 years, 82.4% of the population had abdominal obesity and 84.1% were over-weight or obese. The prevalence of hypertension, dysglycaemia and hypercholesterolaemia was 66.2%, 47.1% and 83% respectively …. A low educational level was associated with a high prevalence of cardiovascular risk factors
Peryt et al. (1992) Mechanism of antimutagenicity of wheat sprout extracts
in this paper we have demonstrated that wheat sprout extract, which has been shown to be antimutagenic towards benzo[a]pyrene (BP) …. The strong inhibition of BP mutagenicity and BP metabolism with non-chlorophyllic wheat sprout extract suggests that chlorophyll is not the main compound responsible for the antimutagenic activity of wheat sprout extract …. suggests that antimutagenic compound(s) contained in the wheat sprout extract belong(s) to this family of flavonoids
Giulivi et al. (2010) Mitochondrial Dysfunction in Autism
In this exploratory study, children with autism were more likely to have mitochondrial dysfunction, mtDNA overreplication, and mtDNA deletions than typically developing children.
Godfrey et al. (2003) Apolipoprotein E genotyping as a potential biomarker for mercury neurotoxicity
Apolipoprotein-E (apo-E) genotyping has been investigated as an indicator of susceptibility to heavy metal (i.e., lead) neurotoxicity. Moreover, the apo-E epsilon (epsilon)4 allele is a major risk factor for neurodegenerative conditions, including Alzheimer’s disease (AD) …. Dental amalgam is the greatest source of mercury in the general population and brain, blood and urine mercury levels increase correspondingly with the number of amalgams and amalgam surfaces in the mouth …. Apo-E genotyping warrants investigation as a clinically useful biomarker for those at increased risk of neuropathology, including AD, when subjected to long-term mercury exposures
Davis et al. (2007) Recommendations for prevention of childhood obesity
children and adolescents is obesity prevention-today, and as they age into adulthood. In this report, we review the most recent evidence regarding many behavioral and practice interventions related to childhood obesity …. sweetened beverage intake is related to obesity among children …. obese children and adolescents are more likely to skip breakfast than their leaner counterparts …. Adolescent sedentary behavior is correlated with parental sedentary behavior …. The evidence is strong that daily moderate/vigorous physical activity helps reduce adiposity in overweight/obese youths
